
Laboratory of Pathophysiology
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Cristina Ibarra
Principal Investigator, Conicet
Full Professor, FMED, UBA
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Our research group studies the physiopathological mechanisms that trigger diarrheas caused by Enterohemorrhagic Escherichia coli (EHEC) and the action of Shiga toxin (Stx2) and other virulence factors responsible for Hemolytic Uremic Syndrome (HUS), with the purpose of developing new strategies to decrease the incidence of EHEC and the development of HUS.


Members

Adjunct Investigator
Conicet
Action of Stx2 in the kidney.
Use of drugs to prevent renal damage.
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Adjunct Investigator
Conicet
Innovative developments for the diagnosis, treatment, and prevention of HUS.
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Adjunct Professor
FMED, UBA
PI Pathology Section
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Teaching Assistant
FMED, UBA
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Doctoral Fellow
Conicet
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Doctoral Fellow
Conicet
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Doctoral Fellow
Conicet
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Internship
FMED – UBA
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Internship
FMED – UBA
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Selected Publications
- Cytotoxic effects of Shiga toxin-2 on human extravillous trophoblast cell lines Scalise ML, Amaral MM, Reppetti J, Damiano AE, Ibarra C, Sacerdoti F. 2019 Jan 1. pii: REP-18-0581.R1.
- Podocyturia in paediatric patients with Fabry disease Liern M, Collazo A, Valencia M, Fainboin A, Isse L, Costales-Collaguazo C, Ochoa F, Vallejo G, Zotta E. Nefrologia 2019 Mar-Apr;39(2):177-183
- Exposure to environmental concentrations of hexachlorobenzene induces alterations associated with endometriosis progression in a rat model. Chiappini F, Sánchez M, Miret N, Cocca C, Zotta E, Ceballos L, Pontillo C, Bilotas M, Randi A. Food Chem Toxicol. 2019 Jan;123:151-161.
- Trophoblast VIP deficiency entails immune homeostasis loss and adverse pregnancy outcome in mice. Hauk V, Vota D, Gallino L, Calo G, Paparini D, Merech F, Ochoa F, Zotta E, Ramhorst R, Waschek J, Leirós CP. FASEB J. 2019 Feb; 33(2):1801-1810.
- Early decrease in the podocalyxin to synaptopodin ratio in urinary Fabry podocytes. Trimarchi H, Canzonieri R, Costales-Collaguazo C, Politei J, Stern A, Paulero M, González-Hoyos I, Schiel A, Rengel T, Forrester M, Lombi F, Pomeranz V, Iriarte R, Muryan A, Zotta E. Clin Kidney J. 2019 Feb;12(1): 53-60.