Laboratorio de Fisiología de la Acción
Directora
Dra. Valeria Della Maggiore
Investigadora Independiente, CONICET
auxiliar docente, UBA
Temas de interés
La actividad del Laboratorio de Fisiología de la Acción está enfocada en el estudio de la neurociencia del comportamiento motor. Utilizamos técnicas de estimulación cerebral no invasivas (TMS o TDCS), la resonancia magnética (MRI) y la electroencefalografía (EEG) para estudiar los mecanismos involucrados en la formación y la persistencia de memorias motoras. A su vez, aplicamos estos conocimientos en intervenciones experimentales que apuntan a potenciar el aprendizaje y la memoria en sujetos normales y pacientes con ACV.
Integrantes
Lic. Pedro Caffaro. Becario doctoral, CONICET [+]
Ing. Florencia Jacobacci, Becaria doctoral, CONICET [+]
Ignacio Gimenez, Becario doctoral, CONICET [+]
Ain Stolkiner, Pasante [+]
Gonzalo Lerner, tesista de Licenciatura [+]
Colaboradores
Dr. Reza Shadmehr, Professor, Dept. of Biomedical Engineering, Johns Hopkins University
Dr. Randy McIntosh, Professor, Rotman Research Institute, University of Toronto.
Dr. Julien Doyon, Professor, Department of Psychology, University of Montreal, Canada.
Dr. Jorge Armony, Professor, McGill University, Montreal, Canada
Dr. Pedro Valdes-Sosa, Profesor, Instituto de Neurociencias, La Habana, Cuba.
Dra. Adriana Conforto, Profesora, USP, Sao Paulo, Brasil.
Dr. Edson Amaro, Profesor, USP, Sao Paulo, Brasil
Dr. Jorge Mazzeo, Facultad de Ingeniería, UBA, Argentina
Dr. Luis Riquelme, Auxiliar docente, UBA, Argentina
Dra. Cecilia Forcatto, Profesora Universidad de Quilmes, Argentina
Ex-Integrantes
Lic. Sofía M. Landi, Tesista Licenciatura
Ingeniera Mariel Bernal, Tesista Ingeniería
Dr. Jorge I. Villalta, Tesis de Doctorado
Claire Landmann, Post Doc
Dra. Sofía McCabe, Post Doc
Dr. Nicolas Gueugneau, Post Doc
Publicaciones destacadas
- Corticolimbic interactions associated with performance on a short-term memory task are modified by age. Della-Maggiore V, Sekuler AB, Grady CL, Bennett PJ, Sekuler R, McIntosh AR. Journal of Neuroscience. 20 (22): 8410-6. Society for Neuroscience, Washington DC (2000).
- Stimulation of the posterior parietal cortex interferes with arm trajectory adjustments during the learning of new dynamics. Della-Maggiore V, Malfait N, Ostry D, Paus T. Journal of Neuroscience, 24(44): 9971-6. Society for Neuroscience, Washington DC (2004).
- Time course of changes in brain activity and functional connectivity associated with long-term adaptation to a rotational transformation. Della-Maggiore V, McIntosh AR. Journal of Neurophysiology, 93(4):2254-62. Amer Physiological Society, Bethesda, MD (2005).
- Motor memory consolidation: Night and Day. Della-Maggiore V. Journal of Neuroscience, 25(40):9067:9068. Society for Neuroscience, Washington DC (2005).
- One week of motor adaptation induces structural changes in primary motor cortex that predict long-term memory one year later. Landi, SM, Baguear, FM, Della-Maggiore V (2011) Journal of Neuroscience, Aug 17;31(33):11808-13.
- Extinction interferes with the retrieval of visuomotor memories through a mechanism involving the sensorimotor cortex. JI Villalta, SM Landi, A Flo, V Della-Maggiore (2013) Cerebral Cortex. 2013 Dec 19.
- The relative influence of goal and kinematics on corticospinal excitability depends on the information provided to the observer. Mc Cabe SI, Villalta JI, Saunier G; Grafton ST, Della-Maggiore V (2014) Cerebral Cortex. 2014 Mar 2.
- Sensorimotor Adaptation: Multiple forms of Plasticity in Motor Circuits. Della-Maggiore V, Landi SM, Villalta JI (2014) Neuroscientist. 2015 Apr;21(2):109-25.
- Direct mapping rather than motor prediction subserves modulation of corticospinal excitability during observation of actions in real time.Gueugneau N, Mc Cabe SI, Villalta JI, Grafton ST, Della-Maggiore V (2015) J Neurophysiology. Mar 25.
- Functional evidence for memory stabilization in sensorimotor adaptation: a 24h resting-state fMRI study. Della-Maggiore V, Villalta JI, Kovecevic N, McIntosh AR (2015) In press in Cerebral Cortex.
Divulgación
Programa de Televisión Cerebro Argentino (TecTV)
Programa de Televisión en C5N Los Enigmas del Cerebro: Cerebro Motor
Financiamiento
PIDDEF(Ministerio de Defensa) 2014-2017; # 17/14: 2016-2018; 2,967,809.25 $
International Network collaboration (QBIN) Pis: Valeria Della-Maggiore & Jorge Armony; collaborators: Julien Doyon, Pedro Valdes-Sosa & Edson Amaro; # Projet RI-1.05; 2016-2017; 100,000 CDN $
PROLAB International collaborative award (International Brain Research Organization) PI: Valeria Della-Maggiore; collaborators: Jorge Mazzeo, Adriana Conforto, Edson Amaro; 2015-2016; 4000 Euros
UBACyT PDE (UBA), # 2016-2017; 75,000 $
PIP (CONICET); # 512; 2012-2014; 36,000$
UBACyT (UBA); # 20020130100750BA; 2014-2017; 6,000 $
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